Concepedia

Fatty Acid Synthase Complex

Fatty Acid Synthase Complex is a multienzyme complex that catalyzes the sequential reactions of fatty acid biosynthesis by integrating multiple catalytic domains within a single polypeptide or associated subunits to facilitate the de novo synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA precursors.

505

Publications

30.3K

Citations

2.3K

Authors

702

Institutions

Publications per year

2017–2026

97

Variants

Fas Complex

Parents

Publications

505

Modular Organization of Genes Required for Complex Polyketide Biosynthesis

Stefano Donadio, Michael J. Staver, James B. McAlpine et al. · Science · 1991 · 909 citations

, , +17

The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

The FASEB Journal · 1994 · 601 citations

, , +17

Exploring drug-induced alterations in gene expression in <i>Mycobacterium tuberculosis</i> by microarray hybridization

Michael R. Wilson, Joseph L. DeRisi, Hans‐Henrik Kristensen et al. · Proceedings of the National Academy of Sciences · 1999 · 555 citations · Full text

, , +14

The Crystal Structure of a Mammalian Fatty Acid Synthase

Timm Maier, Marc Leibundgut, Nenad Ban · Science · 2008 · 510 citations

, , +17

Architecture of Mammalian Fatty Acid Synthase at 4.5 A Resolution

Timm Maier, Simon Jenni, Nenad Ban · Science · 2006 · 396 citations

, , +17

1–5 of 505

Authors

2.3K

  1. SJ
    Salih J. Wakil

    Baylor College of Medicine, United States

    16 publications · 831 citations

    15

    h-index

  2. WT
    Weixi Tian

    University of Chinese Academy of Sciences, China

    13 publications · 636 citations

    11

    h-index

  3. MG
    Martin Grininger

    Goethe University Frankfurt, Germany

    11 publications · 894 citations

    11

    h-index

  4. AK
    Anil K. Joshi

    University of California, Berkeley, United States

    11 publications · 741 citations

    11

    h-index

  5. ES
    Eckhart Schweizer

    Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

    9 publications · 384 citations

    9

    h-index

1–5 of 2.3K

Institutions

702

  1. Johns Hopkins University

    Baltimore, United States

    16 h-index

    61 publications

    4.7K citations

  2. Baylor College of Medicine

    Houston, United States

    15 h-index

    57 publications

    3.5K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    68 publications

    2.7K citations

  4. University of Chinese Academy of Sciences

    Beijing, China

    13 h-index

    51 publications

    1.9K citations

  5. Chinese Academy of Sciences

    Beijing, China

    10 h-index

    34 publications

    2.5K citations

  6. Friedrich-Alexander-Universität Erlangen-Nürnberg

    Erlangen, Germany

    10 h-index

    43 publications

    2K citations

  7. Johns Hopkins Medicine

    Baltimore, United States

    10 h-index

    30 publications

    2.7K citations

  8. Harvard University

    Cambridge, United States

    9 h-index

    30 publications

    5.1K citations

1–8 of 702

Venues

  1. Journal of Biological Chemistry

    JBC · 46 publications · 4.1K citations

    35

    h-index

  2. Biochemical and Biophysical Research Communications

    BBRC · 19 publications · 1.1K citations

    16

    h-index

  3. Archives of Biochemistry and Biophysics

    ABB · 18 publications · 700 citations

    15

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 1.7K citations

    15

    h-index

  5. Biochemistry

    16 publications · 615 citations

    13

    h-index

1–5