Comparative binding of μ and δ selective ligands in whole brain and pons/medulla homogenates from rat: Affinity profiles of fentanyl derivatives

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I

Jacques Glowinski, Leslie L. Iversen · Journal of Neurochemistry · 1966 · 5.4K citations

Life Sciences, Neurobiology, Neuroscience +8

SPECTRUM OF THE μ‐, δ‐ AND κ‐BINDING SITES IN HOMOGENATES OF RAT BRAIN

Maureen Gc Gillan, H. W. Kosterlitz · British Journal of Pharmacology · 1982 · 279 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Separation of opioid analgesia from respiratory depression: evidence for different receptor mechanisms.

Geoffrey Ling, K. Spiegel, Stephen H. Lockhart et al. · Journal of Pharmacology and Experimental Therapeutics · 1985 · 271 citations

Medicine, Pharmacology, Neuropharmacology +15

The use of [³H]‐[<scp>d</scp>‐Pen²,<scp>d</scp>‐Pen⁵]enkephalin as a highly selective ligand for the δ‐binding site

Ron Cotton, H. W. Kosterlitz, Sue Paterson et al. · British Journal of Pharmacology · 1985 · 101 citations · Full text

Medicine, Neuroscience, Pharmacology +16