Concepedia

Lack of effect of metofluthrin and sodium phenobarbital on replicative DNA synthesis and Ki-67 mRNA expression in cultured human hepatocytes

Tomoya Yamada, Hiroko Kikumoto, Brian G. Lake, Satoshi Kawamura

Toxicology Research · 2015 · 27 citations · 23 references

DOI

Concepts

Abstract

High doses of metofluthrin have been shown to produce hepatocellular tumours in rats.

References

23

IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans

Alan R. Boobis, Samuel M. Cohen, Vicki L. Dellarco et al. · Critical Reviews in Toxicology · 2006 · 460 citations

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IPCS Conceptual Framework for Evaluating a Mode of Action for Chemical Carcinogenesis

C. Sonich-Mullin, R.J. Fielder, Jeanette Wiltse et al. · Regulatory Toxicology and Pharmacology · 2001 · 348 citations

, , +14

Induction of CYP2C genes in human hepatocytes in primary culture.

Sabine Gerbal‐Chaloin, Jean‐Marc Pascussi, Lydiane Pichard‐Garcia et al. · PubMed · 2001 · 318 citations

, , +15

Mode of Action in Relevance of Rodent Liver Tumors to Human Cancer Risk

Michael P. Holsapple, H. C. Pitot, Samuel H. Cohen et al. · Toxicological Sciences · 2005 · 264 citations

, , +17

Evaluating the Human Relevance of Chemically Induced Animal Tumors

Samuel M. Cohen · Toxicological Sciences · 2004 · 164 citations

, , +13