Concepedia

Phenobarbital Therapy

Phenobarbital Therapy is a pharmacotherapeutic intervention within pediatric neurologic and antiepileptic treatment regimens that specifically employs phenobarbital, a long-acting barbiturate, to exert anticonvulsant effects through enhancement of GABAergic neurotransmission in the central nervous system.

2.5K

Publications

113.5K

Citations

7.6K

Authors

1.7K

Institutions

Publications per year

2017–2026

131

Parents

Publications

2.5K

ETHOXYRESORUFIN: DIRECT FLUORIMETRIC ASSAY OF A MICROSOMAL O-DEALKYLATION WHICH IS PREFERENTIALLY INDUCIBLE BY 3-METHYLCHOLANTHRENE

M.D. Burke, Richard T. Mayer · Drug Metabolism and Disposition · 1974 · 1.6K citations

, , +17

Comparison of Carbamazepine, Phenobarbital, Phenytoin, and Primidone in Partial and Secondarily Generalized Tonic–Clonic Seizures

Richard H. Mattson, Joyce A. Cramer, Joseph F. Collins et al. · New England Journal of Medicine · 1985 · 1.1K citations

, , +17

Antiepileptic drugs and apoptotic neurodegeneration in the developing brain

Petra Bittigau, Marco Sifringer, Kerstin Genz et al. · Proceedings of the National Academy of Sciences · 2002 · 780 citations · Full text

, , +17

Refractory Status Epilepticus

Stephan A. Mayer, Jan Claassen, Johnny K Lokin et al. · Archives of Neurology · 2002 · 655 citations

, , +14

Phenobarbital Compared with Phenytoin for the Treatment of Neonatal Seizures

Michael J. Painter, Mark S. Scher, Aryeh D. Stein et al. · New England Journal of Medicine · 1999 · 611 citations · Full text

, , +14

1–5 of 2.5K

Authors

7.6K

  1. WL
    Wolfgang Löscher

    University of Veterinary Medicine Hannover, Foundation, Germany

    16 publications · 835 citations

    15

    h-index

  2. JY
    Joseph Yanai

    Hebrew University of Jerusalem, Israel

    14 publications · 426 citations

    13

    h-index

  3. WL
    Wayne Levin

    La Roche College, United States

    13 publications · 1.5K citations

    13

    h-index

  4. RG
    Ronald G. Thurman

    University of North Carolina at Chapel Hill, United States

    14 publications · 607 citations

    12

    h-index

  5. CA
    Charles A. Blake

    University of Nebraska Medical Center, United States

    10 publications · 242 citations

    10

    h-index

1–5 of 7.6K

Institutions

1.7K

  1. University of Washington

    Seattle, United States

    31 h-index

    123 publications

    8.6K citations

  2. National Institutes of Health

    Bethesda, United States

    27 h-index

    116 publications

    8.5K citations

  3. Harvard University

    Cambridge, United States

    22 h-index

    94 publications

    6.8K citations

  4. Karolinska Institutet

    Stockholm, Sweden

    21 h-index

    78 publications

    5.1K citations

  5. University of Wisconsin–Madison

    Madison, United States

    20 h-index

    69 publications

    3K citations

  6. University of Michigan

    Ann Arbor, United States

    20 h-index

    63 publications

    3.7K citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    19 h-index

    56 publications

    3K citations

  8. University College London

    London, United Kingdom

    19 h-index

    57 publications

    2.4K citations

1–8 of 1.7K

Venues

  1. Epilepsia

    125 publications · 7K citations

    50

    h-index

  2. PubMed

    Repository · 220 publications · 8.2K citations

    44

    h-index

  3. 42

    h-index

  4. Journal of Biological Chemistry

    JBC · 49 publications · 5.2K citations

    39

    h-index

  5. Molecular Pharmacology

    56 publications · 2.5K citations

    33

    h-index

1–5