Impact of Phospholipase A2 Group IIa Gene Polymorphism on Phenotypic Features of Patients with Familial Adenomatous Polyposis

Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients

Isamu Nishisho, Yusuke Nakamura, Yasuo Miyoshi et al. · Science · 1991 · 1.9K citations

Oncology, Chromosome 5Q21, Medicine +12

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

Melina MacPhee, Kenneth P. Chepenik, Rebecca A. Liddell et al. · Cell · 1995 · 564 citations · Full text

Signal Transduction, Signaling Pathway, Apcmin-induced Intestinal Neoplasia +9

Familial adenomatous polyposis: desmoid tumours and lack of ophthalmic lesions (CHRPE) associated with APC mutations beyond codon 1444

Reiner Caspari, S Olschwang, Waltraut Friedl et al. · Human Molecular Genetics · 1995 · 367 citations

Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients.

Hiroki Nagase, Yoko Miyoshi, Akira Horii et al. · PubMed · 1992 · 346 citations

Germ-line Mutations, Engineering, Genetics +17

Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis

Robert T. Cormier, Karen Hong, Richard B. Halberg et al. · Nature Genetics · 1997 · 324 citations

Signal Transduction, Intestinal Tumorigenesis, Pathology +5