Concepedia

Modifier Gene Analysis

Modifier Gene Analysis is a genetic methodology within forward genetics that identifies and characterizes secondary genes altering the phenotypic expression of a primary mutation, thereby revealing genetic interactions and regulatory relationships.

79

Publications

4.7K

Citations

680

Authors

294

Institutions

Publications per year

2017–2026

8

Parents

Publications

79

Digenic Inheritance of Early-Onset Glaucoma: CYP1B1, a Potential Modifier Gene

Andrea L. Vincent, Gail Billingsley, Yvonne M. Buys et al. · The American Journal of Human Genetics · 2002 · 308 citations · Full text

, , +12

A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.

G Lombard-Platet, Stéphane Savary, Claude‐Olivier Sarde et al. · Proceedings of the National Academy of Sciences · 1996 · 226 citations

, , +13

Genome-Wide Gene-Environment Study Identifies Glutamate Receptor Gene GRIN2A as a Parkinson's Disease Modifier Gene via Interaction with Coffee

Taye H. Hamza, Honglei Chen, Erin M. Hill‐Burns et al. · PLoS Genetics · 2011 · 224 citations · Full text

, , +17

Identical Mutation in Patients with Limb Girdle Muscular Dystrophy Type 2B Or Miyoshi Myopathy Suggests a Role for Modifier Gene(s)

Tracey Weiler, R. Bashir, Louise V.B. Anderson et al. · Human Molecular Genetics · 1999 · 179 citations

, , +16

Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect

Marzena Maka, C. Claus Stolt, Michael Wegner · Developmental Biology · 2004 · 167 citations

, , +8

1–5 of 79

Authors

680

  1. GR
    Garry R. Cutting

    Johns Hopkins University, United States

    3 publications · 215 citations

    3

    h-index

  2. AF
    Antônio Fernando Ribeiro

    Universidade Estadual de Campinas (UNICAMP), Brazil

    2 publications · 50 citations

    2

    h-index

  3. MC
    Mary Corey

    Hospital for Sick Children, Canada

    2 publications · 122 citations

    2

    h-index

  4. SM
    Scott M. Blackman

    Johns Hopkins University, United States

    2 publications · 82 citations

    2

    h-index

  5. GL
    Gérald Le Gac

    Inserm, France

    2 publications · 224 citations

    2

    h-index

1–5 of 680

Institutions

294

  1. Inserm

    Paris, France

    6 h-index

    58 publications

    4.9K citations

  2. Johns Hopkins University

    Baltimore, United States

    5 h-index

    21 publications

    937 citations

  3. Johns Hopkins Medicine

    Baltimore, United States

    4 h-index

    12 publications

    493 citations

  4. Hospital for Sick Children

    Toronto, Canada

    4 h-index

    27 publications

    3.5K citations

  5. Sorbonne Université

    Paris, France

    3 h-index

    29 publications

    2.7K citations

  6. University of Cincinnati Medical Center

    Cincinnati, United States

    3 h-index

    3 publications

    264 citations

  7. University of Toronto

    Toronto, Canada

    3 h-index

    12 publications

    2.2K citations

  8. University of Milan

    Milan, Italy

    3 h-index

    6 publications

    163 citations

1–8 of 294

Venues

  1. PubMed

    Repository · 6 publications · 245 citations

    6

    h-index

  2. Blood

    3 publications · 284 citations

    3

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 333 citations

    3

    h-index

  4. Human Genetics

    2 publications · 107 citations

    2

    h-index

  5. PLoS Genetics

    2 publications · 325 citations

    2

    h-index

1–5