Hiroki Nagase

Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.

Yoko Miyoshi, Hitoshi Ando, Hiroki Nagase et al. · Proceedings of the National Academy of Sciences · 1992 · 558 citations · Full text

Apc Mutation, Ribonuclease Protection Analysis, Germ-line Mutations +12

Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients.

Hiroki Nagase, Yoko Miyoshi, Akira Horii et al. · PubMed · 1992 · 346 citations

Germ-line Mutations, Engineering, Genetics +17

Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression

Fei Song, Joseph F. Smith, Makoto Kimura et al. · Proceedings of the National Academy of Sciences · 2005 · 333 citations · Full text

Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

Amanda E. Toland, Paraskevi Briassouli, John P. de Koning et al. · Nature Genetics · 2003 · 320 citations

Oncology, Medicine, Pathology +8

The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer.

Akira Horii, Shuichi Nakatsuru, Yasuo Miyoshi et al. · PubMed · 1992 · 227 citations

Cancer Pathology, Genetics, Pathology +19