Nuclear Access and Action of Notch In Vivo

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Andrea H. Brand, Norbert Perrimon · Development · 1993 · 9.7K citations

A short amino acid sequence able to specify nuclear location

Daniel Kalderon, Bruce Roberts, William D. Richardson et al. · Cell · 1984 · 2.6K citations

Biochemistry, Structural Bioinformatics, Protein Folding +10

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper, Paul Säftig, Katleen Craessaerts et al. · Nature · 1998 · 1.8K citations

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Biology +9

Signalling downstream of activated mammalian Notch

Sophie Jarriault, Christel Brou, Frédérique Logeat et al. · Nature · 1995 · 1.4K citations

Developmental Biology, Signal Transduction, Signaling Pathway +8

GAL4-VP16 is an unusually potent transcriptional activator

Ivan Sadowski, Jun Ma, Steven J. Triezenberg et al. · Nature · 1988 · 1.4K citations

Potent Transcriptional Activator, Transcriptional Regulation, Molecular Regulation +6