Concepedia

Synphilin-1 exhibits trophic and protective effects against Rotenone toxicity

Xiaopeng Li, Zhong Wu Liu, Kellie L. Tamashiro, B. Shi, D.D. Rudnicki, C A Ross, Timothy H. Moran, W. W. Smith

Neuroscience · 2009 · 21 citations · 25 references

DOI

Concepts

References

25

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

Mihael H. Polymeropoulos, Christian Lavedan, Elisabeth Leroy et al. · Science · 1997 · 8.2K citations

, , +17

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Ranjita Betarbet, Todd Sherer, Gillian M. MacKenzie et al. · Nature Neuroscience · 2000 · 3.7K citations

, , +12

Parkin ubiquitinates the α-synuclein–interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

Kenny K. K. Chung, Yi Zhang, Yuji Tanaka et al. · Nature Medicine · 2001 · 753 citations

, , +15

Parkin Protects against the Toxicity Associated with Mutant α-Synuclein

Leonard Petrucelli, Casey O’Farrell, Paul J. Lockhart et al. · Neuron · 2002 · 551 citations · Full text

, , +16

Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions

Simone Engelender, Zachary Kaminsky, Xin Guo et al. · Nature Genetics · 1999 · 491 citations

, , +13