Concepedia

SFlt-1 Elevates Blood Pressure by Augmenting Endothelin-1-Mediated Vasoconstriction in Mice

Fouad Amraoui, Léon J. A. Spijkers, Hajar Hassani Lahsinoui, Liffert Vogt, Joris van der Post, Stephan L.M. Peters, Gijs Afink, Carrie Ris‐Stalpers, Bert‐Jan H. van den Born

PLoS ONE · 2014 · 59 citations · 33 references

DOIFull text

Open access

Abstract

VEGF inhibition augments the pressor response to ET-1. The cyclooxygenase-thromboxane signaling route downstream of ET-1 might be a possible target to prevent BP elevation during VEGF inhibition.

References

33

NIH Image to ImageJ: 25 years of image analysis

Caroline A Schneider, Wayne Rasband, Kevin W. Eliceiri · Nature Methods · 2012 · 62.8K citations · Full text

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Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

Sharon E. Maynard, Jiang-Yong Min, Jaime R. Merchan et al. · Journal of Clinical Investigation · 2003 · 3.9K citations · Full text

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Circulating Angiogenic Factors and the Risk of Preeclampsia

Richard J. Levine, Cong Qian, Lucinda J. England et al. · New England Journal of Medicine · 2004 · 3.5K citations · Full text

Circulating angiogenic factors and the risk of preeclampsia*

Obstetrics and Gynecology · 2004 · 2.6K citations

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VEGF Inhibition and Renal Thrombotic Microangiopathy

Vera Eremina, J. Ashley Jefferson, Jolanta Kowalewska et al. · New England Journal of Medicine · 2008 · 1.5K citations · Full text

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