Survivin as prognostic factor in squamous cell carcinoma of the oral cavity

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

Mitophagy, Signal Transduction, Mitochondrial Function +8

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

Grazia Ambrosini, Colette Adida, Dario C. Altieri · Nature Medicine · 1997 · 3.2K citations

Tumor Biology, Oncogenic Agent, Novel Anti-apoptosis Gene +8

X-linked IAP is a direct inhibitor of cell-death proteases

Quinn L. Deveraux, Ryōsuke Takahashi, Guy S. Salvesen et al. · Nature · 1997 · 1.9K citations

Protein Function, Apoptosis, Autophagy +5

Control of apoptosis and mitotic spindle checkpoint by survivin

Fengzhi Li, Grazia Ambrosini, Emily Chu et al. · Nature · 1998 · 1.9K citations

Cell Division, Apoptosis, Mitotic Spindle Checkpoint +6

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

Ingo Tamm, Yi Wang, Edward A. Sausville et al. · PubMed · 1998 · 1.3K citations

Apoptosis Protein, Apoptosis, Cell Death +18