Concepedia

Overexpression of EphA2, MMP‐9, and MVD‐CD34 in hepatocellular carcinoma: Implications for tumor progression and prognosis

Pu Yang, Weijie Yuan, Jiantai He, Jiwei Wang, Li Yu, Xin Jin, Yu Hu, Mingmei Liao, Zihua Chen, Zhang Yang-de

Hepatology Research · 2009 · 73 citations · 24 references

DOIFull text

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Abstract

Overexpressions of EphA2 and MMP-9 relate to tumor progression, metastasis, and prognosis in HCC. The present study suggests that EphA2 is associated with key mediators of angiogenesis and invasion.

References

24

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

Gabriele Bergers, Rolf A. Brekken, Gerald McMahon et al. · Nature Cell Biology · 2000 · 2.8K citations · Full text

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Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis

Hiroaki Nozawa, Christopher Chiu, Douglas Hanahan · Proceedings of the National Academy of Sciences · 2006 · 911 citations · Full text

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The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

Kazushige Ogawa, Renata Pasqualini, Richard Lindberg et al. · Oncogene · 2000 · 382 citations

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Tumor Microvessel Density as a Predictor of Recurrence After Resection of Hepatocellular Carcinoma: A Prospective Study

Ronnie Tung‐Ping Poon, Irene Oi‐Lin Ng, Cecilia Lau et al. · Journal of Clinical Oncology · 2002 · 284 citations

Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells.

Hiroshi Sato, Yutaka Kida, M. Mai et al. · PubMed · 1992 · 227 citations