The effects of calpeptin (a calpain specific inhibitor) on agonist induced microparticle formation from the platelet plasma membrane

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Harry Towbin, T. Staehelin, J. Gordon · Proceedings of the National Academy of Sciences · 1979 · 53.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

BS Coller, EI Peerschke, LE Scudder et al. · Blood · 1983 · 463 citations

Medicine, Pharmacology, Cell Signaling +16

Loss of membrane phospholipid asymmetry in platelets and red cells may be associated with calcium-induced shedding of plasma membrane and inhibition of aminophospholipid translocase

Paul Comfurius, Joan M. Senden, Roland H. J. Tilly et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1990 · 283 citations

Life Sciences, Biochemistry, Cell Biology +11

Synthesis of a new cell penetrating calpain inhibitor (calpeptin)

Toshimasa Tsujinaka, Yuki Kajiwara, Junichi Kambayashi et al. · Biochemical and Biophysical Research Communications · 1988 · 247 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9