A Case Control Study on the Contribution of Factor V-Leiden, Prothrombin G20210A, and MTHFR C677T Mutations to the Genetic Susceptibility of Deep Venous Thrombosis

Mutation in blood coagulation factor V associated with resistance to activated protein C

Rogier M. Bertina, Bobby P. C. Koeleman, Ted Koster et al. · Nature · 1994 · 3.8K citations

Medicine, Genetics, Hematology +14

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis

SR Poort, FR Rosendaal, PH Reitsma et al. · Blood · 1996 · 3.1K citations · Full text

Medicine, Genetics, Molecular Genetics +15

World distribution of factor V Leiden

David C. Rees, Michael J. Cox, J. B. Clegg · The Lancet · 1995 · 1.2K citations

Medicine, Genetics, Genetic Epidemiology +10

High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance) [see comments]

FR Rosendaal, Ted Koster, PH Reitsma · Blood · 1995 · 1K citations

Medicine, Genetics, Hematology +16

Geographic Distribution of the 20210 G to A Prothrombin Variant

Carine J.M. Doggen, Ariella Zivelin, Valder R. Arruda et al. · Thrombosis and Haemostasis · 1998 · 702 citations · Full text

Medicine, Genetics, Molecular Genetics +17