Chronological analysis of caloric restriction-induced alteration of fatty acid biosynthesis in white adipose tissue of rats

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Peter Tontonoz, Erding Hu, Bruce M. Spiegelman · Cell · 1994 · 3.5K citations

Transcriptional Regulation, Cell Signaling, Physiology +10

Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue

Matthias Blüher, Barbara B. Kahn, C. Ronald Kahn · Science · 2003 · 1.3K citations

Aging, Insulin Receptor, Caloric Restriction +16

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

Shinichi Someya, Wei Yu, William C. Hallows et al. · Cell · 2010 · 1.1K citations · Full text

Caloric Restriction, Age-related Hearing Loss, Sirt3 Mediates Reduction +7

Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance

Matthias Blüher, M.Dodson Michael, Odile D. Peroni et al. · Developmental Cell · 2002 · 806 citations · Full text

Obesity, Metabolic Syndrome, Insulin Signaling +12

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

Jay D. Horton, Iichiro Shimomura, Matthew Brown et al. · Journal of Clinical Investigation · 1998 · 704 citations · Full text

Metabolic Syndrome, Cholesterol Biosynthesis, Biochemistry +15