A Cross-Sectional Characterization of Insulin Resistance by Phenotype and Insulin Clamp in East Asian Americans with Type 1 and Type 2 Diabetes

William C. Hsu, Eyiuche Okeke, Sophia Cheung, Hillary A. Keenan, Tracy Tsui, Kyle Cheng, George L. King

PLoS ONE · 2011 · 24 citations · 18 references

DOIFull text

Open access

Abstract

Type 2 diabetes in Asian Americans was associated with insulin resistance despite having low BMI as type 1 diabetes, suggesting a potential role for targeting insulin resistance apart from weight loss. Adipocyte fatty acid binding protein, strongly associated with insulin resistance, independent of adiposity in the young Asian American population, may potentially serve as a biomarker to identify at-risk individuals. Larger studies are needed to confirm this finding.

References

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