Indoxyl Sulfate Induces Endothelial Cell Senescence by Increasing Reactive Oxygen Species Production and p53 Activity

Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients

Fellype Carvalho Barreto, Daniela Veit Barreto, Sophie Liabeuf et al. · Clinical Journal of the American Society of Nephrology · 2009 · 887 citations · Full text

The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair

Laetitia Dou, Emilie Bertrand, Claire Cérini et al. · Kidney International · 2004 · 468 citations · Full text

Inflammation, Urology, Anti-inflammatory +10

Indoxyl sulfate, a circulating uremic toxin, stimulates the progression of glomerular sclerosis.

Takashi Niwa, Michihito Ise · PubMed · 1994 · 410 citations

The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells

Laetitia Dou, Noémie Jourde‐Chiche, Valérie Faure et al. · Journal of Thrombosis and Haemostasis · 2007 · 405 citations · Full text

Inflammation, Endothelial Cells, Biochemistry +8

Elevation of circulating endothelial microparticles in patients with chronic renal failure

Valérie Faure, Laetitia Dou, Florence Sabatier et al. · Journal of Thrombosis and Haemostasis · 2006 · 318 citations

Hemodialysis, Urology, Renal Function +11