Concepedia

The genetics of the Lp Antigen

Charles F. Sing, Jane S. Schultz, Donald C. Shreffler

Annals of Human Genetics · 1974 · 82 citations · 15 references

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Concepts

Abstract

SUMMARY Several genetic models were considered to explain the distribution of qualitatively positive and negative children in 204 Caucasian families. A model which best describes the inheritance of the Lp antigenic expression involves a major genetic locus which distinguishes two overlapping continuously distributed modes of quantitative activity.

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