Stereocontrolled syntheses of chiral and racemic key intermediates to thienamycin from d-allo-threonine and trans-crotonic acid

Thienamycin, a new .BETA.-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties.

Jean S. Kahan, Frederick M. Kahan, Robert T. Goegelman et al. · The Journal of Antibiotics · 1979 · 507 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Sodium Cyanoborohydride - A Highly Selective Reducing Agent for Organic Functional Groups

Clinton F. Lane · Synthesis · 1975 · 463 citations

Natural Sciences, Chemistry, Bioorganic Chemistry +12

A stereocontrolled synthesis of (+)-thienamycin

T. N. SALZMANN, Ronald W. Ratcliffe, B. G. CHRISTENSEN et al. · Journal of the American Chemical Society · 1980 · 388 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

Structure and absolute configuration of thienamycin

G. ALBERS‐SCHOENBERG, Byron H. Arison, Otto D. Hensens et al. · Journal of the American Chemical Society · 1978 · 299 citations

Pharmacy, Chemistry, Medicinal Chemistry +8

Synthesis of Carbapenem Antibiotics

Tetsuji Kametani, Keiichiro Fukumoto, Masataka Ihara · Heterocycles · 1982 · 130 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +3