The protein tyrosine phosphatase SHP-2 is required for EGFRvIII oncogenic transformation in human glioblastoma cells

Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

Ingo K. Mellinghoff, Maria Y. Wang, Igor Vivanco et al. · New England Journal of Medicine · 2005 · 1.4K citations · Full text

Crystal Structure of the Tyrosine Phosphatase SHP-2

Peter Hof, Scott Pluskey, Sirano Dhe‐Paganon et al. · Cell · 1998 · 990 citations · Full text

Crystal Structure, Biochemistry, Protein X-ray Crystallography +3

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity.

Ryo Nishikawa, Xiang-Dong Ji, R. Christopher Harmon et al. · Proceedings of the National Academy of Sciences · 1994 · 926 citations

Mutant Egfr, Pathology, High-grade Gliomas +16

SH2-Containing Phosphotyrosine Phosphatase as a Target of Protein-Tyrosine Kinases

Gen‐Sheng Feng, Chi-Chung Hui, Tony Pawson · Science · 1993 · 669 citations

Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors.

David K. Moscatello, Marina Holgado-Madruga, Andrew K. Godwin et al. · PubMed · 1995 · 641 citations

Tumor Biology, Frequent Expression, Tumoral Pathology +15