NLRP3 polymorphisms are associated with late-onset Alzheimer's disease in Han Chinese

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 27.8K citations · Full text

Common SNPs explain a large proportion of the heritability for human height

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Quantitative Genetics, Common Snps, Genotype-phenotype Association +11

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka, Markus P. Kummer, Andrea Stutz et al. · Nature · 2012 · 2.8K citations · Full text

App/ps1 Mice, Neurodegenerative Diseases, Signal Transduction +11

Variant of <i>TREM2</i> Associated with the Risk of Alzheimer's Disease

Thorlákur Jónsson, Hreinn Stefánsson, Stacy Steinberg et al. · New England Journal of Medicine · 2012 · 2.5K citations · Full text

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Annett Halle, Veit Hornung, Gabor C. Petzold et al. · Nature Immunology · 2008 · 2.4K citations · Full text

Inflammation, Nalp3 Inflammasome, Innate Immune System +7