Science · 1965 · 55 citations · 4 references
Life SciencesImmunologyImmunogeneticsAntibody-antigen RecognitionImmune ResponseImmune System ModelingAntibody Cross-reactivityAntigen-specific Antibody ResponsesImmune Cross-reactivityImmunoassay Cross-reactivityImmunological ModelingSerological Comparison
Transformations of serologic reaction patterns into verbal codes are analyzed. Two equally consistent and complementary models are compared. A model based on the assumption that antibodies are complex (cross-reacting) permits simpler, more uniform, and less prejudicing interpretations of immunogenetic systems than when antibodies are regarded as simple (specific).
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Relationship of Human Anti-lipoprotein Allotypic Sera
Jan Hirschfeld, Baruch S. Blumberg, A. C. Allison · Nature · 1964 · 24 citations
Shape of the Precipitate in Immunoelectrophoresis
Jan Hirschfeld · Nature · 1960 · 18 citations