Involvement of a natural transport system in the process of efflux-mediated drug resistance in Mycobacterium smegmatis

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Stewart T. Cole, Roland Brosch, Julian Parkhill et al. · Nature · 1998 · 7.8K citations · Full text

Pulmonary Tuberculosis, Complete Genome Sequence, Mycobacterium Tuberculosis +10

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3K citations

Gene Amplification, Tumor Microenvironment, Oncogenic Agent +15

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

Chang-jie Chen, Janice E. Chin, Kazumitsu Ueda et al. · Cell · 1986 · 1.9K citations

Antimicrobial Resistance Gene, Multidrug-resistant Human Cells, Health Sciences +11

Human Multidrug-Resistant Cell Lines: Increased <i>mdr</i> 1 Expression Can Precede Gene Amplification

Donglai Shen, Antonio Tito Fojo, Janice E. Chin et al. · Science · 1986 · 604 citations

Engineering, Mdr1 Mrna, Cancer Biology +17

Efflux of Chloroquine from <i>Plasmodium falciparum</i> : Mechanism of Chloroquine Resistance

Donald J. Krogstad, Ilya Y. Gluzman, Dennis E. Kyle et al. · Science · 1987 · 523 citations

Antiparasitic Agent, Malaria, Chloroquine Resistance +17