Concepedia

Polymeric black tea polyphenols inhibit mouse skin chemical carcinogenesis by decreasing cell proliferation

Rachana Patel, Rajesh Krishnan, Asha G. Ramchandani, Girish B. Maru

Cell Proliferation · 2008 · 36 citations · 30 references

DOIFull text

Open access

Abstract

PBP-2 was observed to be the most potent polymeric polyphenol fraction and PBP-4 and PBP-5 showed only marginal activity, whereas PBP-1 and PBP-3 displayed intermediate efficacies. In conclusion, the protective effects of PBP fractions could be attributed to inhibition of TPA-induced cellular proliferation.

References

30

Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasms

Peter A. Hall, David A. Levison, Amanda L. Woods et al. · The Journal of Pathology · 1990 · 1.5K citations

, , +15

Anthocyanin‐ and hydrolyzable tannin‐rich pomegranate fruit extract modulates MAPK and NF‐κB pathways and inhibits skin tumorigenesis in CD‐1 mice

Farrukh Afaq, Mohammad Saleem, Christian G. Krueger et al. · International Journal of Cancer · 2004 · 433 citations

Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion

Matthew R. Young, Jian Jian Li, Mercedes Rincón et al. · Proceedings of the National Academy of Sciences · 1999 · 381 citations · Full text

THE INDUCTION OF ORNITHINE DECARBOXYLASE AS AN EARLY, POSSIBLY OBLIGATORY EVENT IN MOUSE SKIN CARCINOGENESIS

T. G. Brien · 1976 · 355 citations

, , +7

The antioxidant conundrum in cancer.

Harold E. Seifried, Sharon S. McDonald, Darrell E. Anderson et al. · PubMed · 2003 · 230 citations

, , +18