Prediction of oral drug absorption in humans by theoretical passive absorption model

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.8K citations

Health Sciences, Medicine, Physiology +9

Physicochemical High Throughput Screening:  Parallel Artificial Membrane Permeation Assay in the Description of Passive Absorption Processes

Manfred Kansy, Frank Senner, Klaus Gubernator · Journal of Medicinal Chemistry · 1998 · 1.3K citations

Pharmaceutical Science, Engineering, Quantitative Pharmacology +21

In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth

Shiyin Yee · Pharmaceutical Research · 1997 · 1K citations

MDCK (Madin-Darby Canine Kidney) Cells: A Tool for Membrane Permeability Screening

Jennifer D. Irvine, Lori H. Takahashi, Karen Lockhart et al. · Journal of Pharmaceutical Sciences · 1999 · 956 citations

AHFS Drug Information

Gerald K. McEvoy · Oncology Issues · 1994 · 892 citations

Preclinical Therapeutics, Therapeutic Guidelines, Pharmacotherapy +22