An oligopeptide ligand-mediated therapeutic gene nanocomplex for liver cancer-targeted therapy

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations · Full text

Engineering, In Vivo Gene Therapy, Several Polycations +20

Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle

W.T. Godbey, Kenneth K. Wu, Antonios G. Mikos · Journal of Biomedical Materials Research · 1999 · 817 citations

Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics

Zonghai Li, Ruijiao Zhao, Xianghua Wu et al. · The FASEB Journal · 2005 · 412 citations

Tumor Xenografts, Targeted Delivery, Peptide Engineering +22

Gene transfer with lipospermines and polyethylenimines

Jean-Serge Rémy, Bassima Abdallah, Maria Antonietta Zanta et al. · Advanced Drug Delivery Reviews · 1998 · 225 citations

Engineering, Genetic Engineering, Synthetic Biology +5

Poly(amidoamine) dendrimer–drug conjugates with disulfide linkages for intracellular drug delivery

Yunus E. Kurtoglu, Raghavendra S. Navath, Bing Wang et al. · Biomaterials · 2009 · 223 citations · Full text

Nanomedicine, Drug Targeting, Engineering +10