Lihua Lai

Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

Jia Xiong, Jia He, Jun Zhu et al. · Molecular Cell · 2022 · 676 citations

Tumor Biology, Tumor-infiltrating Myeloid Cells, Medicine +6

MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN

Yang Liu, Lihua Lai, Qing‐Yun Chen et al. · The Journal of Immunology · 2012 · 274 citations

Inducible MicroRNA-223 Down-Regulation Promotes TLR-Triggered IL-6 and IL-1β Production in Macrophages by Targeting STAT3

Qingyun Chen, Hui Wang, Yang Liu et al. · PLoS ONE · 2012 · 271 citations · Full text

Innate Immune System, Immunology, Immune Regulation +17

Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model

Lihua Lai, Qihong Fu, Yang Liu et al. · Acta Pharmacologica Sinica · 2012 · 220 citations · Full text

Tumor Biology, Breast Oncology, Oncology +8

APOε4 is associated with enhanced in vivo innate immune responses in human subjects

Stephen C. Gale, Li Gao, Carmen Mikacenic et al. · Journal of Allergy and Clinical Immunology · 2014 · 182 citations · Full text

Inflammation, Molecular Immunology, Autoimmune Disease +12