Persistent Heteroplasmy of a Mutation in the Human mtDNA Control Region: Hypermutation as an Apparent Consequence of Simple-Repeat Expansion/Contraction

Sequence and organization of the human mitochondrial genome

Stephen K. Anderson, Alan T. Bankier, B. G. Barrell et al. · Nature · 1981 · 9.7K citations

Medicine, Genetics, Molecular Genetics +12

Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

Kenneth R. Tindall, Thomas A. Kunkel · Biochemistry · 1988 · 810 citations

Life Sciences, Molecular Biology, Dna Replication +9

Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC

Steven J. Laken, Gloria M. Petersen, Stephen B. Gruber et al. · Nature Genetics · 1997 · 689 citations

Medicine, Genetics, Oncology +14

Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs.

Satoshi Horai, Kenji Hayasaka, R Kondo et al. · Proceedings of the National Academy of Sciences · 1995 · 596 citations

Life Sciences, Biology, Evolutionary Biology +17

A high observed substitution rate in the human mitochondrial DNA control region

Thomas J. Parsons, David Muniec, Kevin M. Sullivan et al. · Nature Genetics · 1997 · 499 citations

Medicine, Genetics, Molecular Genetics +10