Concepedia

Conditionally replicative adenovirus driven by the human telomerase promoter provides broad-spectrum antitumor activity without liver toxicity

John Irving, Zhuo Wang, Sandra Powell, Chris O’Sullivan, Michael Mok, Brian J. Murphy, Lisa Cardoza, Jane Lebkowski, Anish Sen Majumdar

Cancer Gene Therapy · 2004 · 87 citations · 43 references

DOI

Concepts

References

43

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

, , +16

Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations

, , +11

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

Toru Nakamura, Gregg B. Morin, Karen Chapman et al. · Science · 1997 · 2.3K citations · Full text

, , +15

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

Matthew Meyerson, Christopher M. Counter, Elinor Ng Eaton et al. · Cell · 1997 · 1.8K citations · Full text

, , +11

Telomerase activity in human germline and embryonic tissues and cells

Woodring E. Wright, Mieczyslaw A. Piatyszek, William E. Rainey et al. · Developmental Genetics · 1996 · 1.4K citations

, , +16