cDNA Cloning, Biological and Immunological Characterization of the Alkaline Serine Protease Major Allergen from <i>Penicillium chrysogenum</i>

Abstract

These results demonstrated that the 34-kD major allergen of P. chrysogenum is an alkaline serine protease. These results also indicated that atopic patients primarily sensitized by either of these prevalent fungal species may develop allergic symptoms by exposure to other environmental fungi due to cross-reacting IgE antibodies against this protease.