Identification of Metabolic Pathways Involved in the Biotransformation of Tolperisone by Human Microsomal Enzymes

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Deborah J. Newton, R W Wang, Anthony Y.H. Lu · Drug Metabolism and Disposition · 1995 · 606 citations

Medicine, Pharmacokinetics, Pharmacology +17

Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man

A. K�pfer, R Preisig · European Journal of Clinical Pharmacology · 1984 · 364 citations

Veterinary Medicine, Genetics, Pharmacology +10

Evidence That CYP2C19 is the Major (S)-Mephenytoin 4'-Hydroxylase in Humans

Jorge Goldstein, M B Faletto, M Romkes-Sparks et al. · Biochemistry · 1994 · 363 citations

Medicine, Biochemistry, Pharmacology +10

Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

Sandra Baldwin, J. C. Bloomer, Graeme Smith et al. · Xenobiotica · 1995 · 298 citations

Medicine, Biochemistry, Pharmacology +17

Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.

Dorothea Sesardic, B. P. Murray, Sandra Murray et al. · British Journal of Clinical Pharmacology · 1990 · 280 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17