Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full <i>in vitro</i> analysis

Timothy D. Warner, Francesco Giuliano, Ivana Vojnovic et al. · Proceedings of the National Academy of Sciences · 1999 · 1.5K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +12

Cyclo-Oxygenase-2 Gene Expression in Neurons Contributes to Ischemic Brain Damage

Shigeru Nogawa, Fangyi Zhang, M. Elizabeth Ross et al. · Journal of Neuroscience · 1997 · 721 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Unexpected Nanomolar Inhibition of Carbonic Anhydrase by COX-2-Selective Celecoxib:  New Pharmacological Opportunities Due to Related Binding Site Recognition

Alexander Weber, Angela Casini, A. Heine et al. · Journal of Medicinal Chemistry · 2003 · 454 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes

Miyako Kato, Shinichi Nishida, Hidero Kitasato et al. · Journal of Pharmacy and Pharmacology · 2001 · 165 citations · Full text

Medicine, Pharmacology, Cellular Pharmacology +14

Cyclo-oxygenase-2 Messenger RNA Induction in Focal Cerebral Ischemia

Yolanda Colląo-Moraes, B S Aspey, Michael Harrison et al. · Journal of Cerebral Blood Flow & Metabolism · 1996 · 129 citations

Life Sciences, Neurobiology, Neuroscience +17