Improved syntheses in the pyrimidine series. 1. The use of pyrimidine‐thiols

Abstract

Abstract Syntheses suitable for large laboratory‐scale working, are described for thiocytosine, cytosine, 4‐hydroxypyrimidinc, 4‐amino‐pyrimidine, 2 : 4‐ and 4: 6‐diaminopyrimidincs, uracil, 4‐amino‐6‐ hydroxypyrunidine and several of their derivatives. The majority of these syntheses start from thiouracil, which has recently become plentiful; all involve replacement of a thiol‐group by −NH 2 , ‐OH or‐H.