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Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms

Hematological MalignancyDistinct MechanismsBone Marrow FailureMalignant Blood DisorderHematologyImmunologyMyeloma CellsNovo Drug ResistanceMedicineCell BiologyTumor MicroenvironmentMyelopoiesis