Concepedia

N10,N11-di-alkylamine indolo[3,2-b]quinolines as hemozoin inhibitors: Design, synthesis and antiplasmodial activity

Marta Figueiras, Kathryn J. Wicht, Sofia A. Santos, João Lavrado, Jiří Gut, Philip J. Rosenthal, Fátima Nogueira, Timothy J. Egan, Rui Moreira, Alexandra Paulo

Bioorganic & Medicinal Chemistry · 2015 · 19 citations · 22 references

DOI

Concepts

References

22

Structure−Function Relationships in Aminoquinolines:  Effect of Amino and Chloro Groups on Quinoline−Hematin Complex Formation, Inhibition of β-Hematin Formation, and Antiplasmodial Activity

Timothy J. Egan, Roger Hunter, Catherine H. Kaschula et al. · Journal of Medicinal Chemistry · 1999 · 311 citations

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The numbers game

Priya Shetty · Nature · 2012 · 306 citations · Full text

, , +5

The Threat of Artemisinin-Resistant Malaria

Arjen M. Dondorp, Rick M. Fairhurst, Laurence Slutsker et al. · New England Journal of Medicine · 2011 · 276 citations

, , +15

A colorimetric high-throughput β-hematin inhibition screening assay for use in the search for antimalarial compounds

Kanyile K. Ncokazi, Timothy J. Egan · Analytical Biochemistry · 2004 · 216 citations

, , +12

The role of neutral lipid nanospheres in <i>Plasmodium falciparum</i> haem crystallization

John M. Pisciotta, Isabelle Coppens, Abhai K. Tripathi et al. · Biochemical Journal · 2007 · 206 citations · Full text

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