Kathryn J. Wicht

Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

Leila S. Ross, Satish K. Dhingra, Sachel Mok et al. · Nature Communications · 2018 · 271 citations · Full text

Life Sciences, Infectious Diseases, Molecular Genetics +17

Structure and drug resistance of the Plasmodium falciparum transporter PfCRT

Jonathan Kim, Yong Zi Tan, Kathryn J. Wicht et al. · Nature · 2019 · 203 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +14

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

Manu Vanaerschot, James M. Murithi, Charisse Flerida A. Pasaje et al. · Cell chemical biology · 2020 · 91 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +17

Identification of β-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity

Rebecca D. Sandlin, Kim Y. Fong, Kathryn J. Wicht et al. · International Journal for Parasitology Drugs and Drug Resistance · 2014 · 82 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis, β-haematin inhibition, and in vitro antimalarial testing of isocryptolepine analogues: SAR study of indolo[3,2-c]quinolines with various substituents at C2, C6, and N11

Ning Wang, Kathryn J. Wicht, Kento Imai et al. · Bioorganic & Medicinal Chemistry · 2014 · 75 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13