CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS

Walther F. Goebel, Oswald T. Avery

The Journal of Experimental Medicine · 1931 · 91 citations · 0 references

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Abstract

1. The p-amino and p-nitromonobenzyl ethers of the specific polysaccharide of Type III Pneumococcus have been prepared. 2. The diazonium ether of the specific polysaccharide has been coupled with serum globulin to yield a specific polysaccharide-protein complex and this complex has been used for immunization. The results of the immunological studies are presented in the following paper.