Concepedia

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

Fiona E McAlpine, Jae‐Kyung Lee, Ashley S. Harms, Kelly A. Ruhn, Mathew Blurton‐Jones, John J. Hong, Pritam Das, Todd E. Golde, Frank M. LaFerla, Salvatore Oddo,

Neurobiology of Disease · 2009 · 281 citations · 66 references

DOIFull text

Open access

Concepts

References

66

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Alison Goate, Marie‐Christine Chartier‐Harlin, Jeremy Brown et al. · Nature · 1991 · 4.6K citations

, , +16

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

, , +12

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

Martin Citron, Tilman Oltersdorf, Christian Haass et al. · Nature · 1992 · 1.7K citations

, , +16

Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP

Jada Lewis, Dennis W. Dickson, Wen-Lang Lin et al. · Science · 2001 · 1.6K citations

, , +15

Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils

Jürgen Götz, F. Chen, Jo Van Dorpe et al. · Science · 2001 · 1.5K citations

, , +14