Bivalency and epitope specificity of a high-affinity IgG3 monoclonal antibody to the Streptococcus Group A carbohydrate antigen. Molecular modeling of a Fv fragment

The protein data bank: A computer-based archival file for macromolecular structures

F. C. Bernstein, Thomas F. Koetzle, G. J. B. Williams et al. · Journal of Molecular Biology · 1977 · 8.6K citations

Structural Bioinformatics, Biomolecular Structure Prediction, Protein Folding +13

A new force field for molecular mechanical simulation of nucleic acids and proteins

Scott J. Weiner, Peter A. Kollman, David A. Case et al. · Journal of the American Chemical Society · 1984 · 4.6K citations

Engineering, Altmetric Attention Score, Molecular Biology +21

An all atom force field for simulations of proteins and nucleic acids

Scott J. Weiner, Peter A. Kollman, Dzung T. Nguyen et al. · Journal of Computational Chemistry · 1986 · 3.4K citations

Dimethyl Ether, Engineering, Atom Force Field +17

Rapid measurement of binding constants and heats of binding using a new titration calorimeter

Thomas Wiseman, Samuel Williston, John F. Brandts et al. · Analytical Biochemistry · 1989 · 2.6K citations

Engineering, Rapid Measurement, Differential Scanning Calorimetry +15

Canonical structures for the hypervariable regions of immunoglobulins

Cyrus Chothia, Arthur M. Lesk · Journal of Molecular Biology · 1987 · 1.4K citations

Immunocytochemical Technique, Protein Folding, Immunology +5