Concepedia

Effect of Combined Interferon-α Induction Therapy and Ribavirin on Chronic Hepatitis C Virus Infection: a Randomized Multicentre Study

Kristian Bjøro, H. Bell, Kjell B. Hellum, Kjell Skaug, N Raknerud, Per Sandvei, S Lund-Tønnesen, B Myrvang

Scandinavian Journal of Gastroenterology · 2002 · 68 citations · 16 references

DOI

Abstract

IFN induction in combination with ribavirin does not increase the sustained virological response rate among patients infected with HCV. Absence of steatosis is an independent predictor of sustained virological response in patients infected with genotypes 1a/1b.

References

16

Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis†

Robert G. Knodell, Kamal G. Ishak, William C. Black et al. · Hepatology · 1981 · 3.6K citations · Full text

Interferon Alfa-2b Alone or in Combination with Ribavirin as Initial Treatment for Chronic Hepatitis C

John G. McHutchison, Stuart C. Gordon, Eugene R. Schiff et al. · New England Journal of Medicine · 1998 · 3.5K citations · Full text

Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus

Thierry Poynard, Patrick Marcellin, Samuel S. Lee et al. · The Lancet · 1998 · 2.3K citations

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Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-α Therapy

Avidan U. Neumann, Nancy P. Lam, Harel Dahari et al. · Science · 1998 · 2.1K citations

Interferon Alfa-2b Alone or in Combination with Ribavirin for the Treatment of Relapse of Chronic Hepatitis C

Gary L. Davis, Rafael Esteban, Vinod K. Rustgi et al. · New England Journal of Medicine · 1998 · 1.3K citations · Full text