Identification of soluble WSX-1 not as a dominant-negative but as an alternative functional subunit of a receptor for an anti-Alzheimer’s disease rescue factor Humanin

WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27

Stefan Pflanz, Linda Hibbert, Jeanine Mattson et al. · The Journal of Immunology · 2004 · 697 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

Yuichi Hashimoto, Takako Niikura, Hirohisa Tajima et al. · Proceedings of the National Academy of Sciences · 2001 · 616 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

Atsunobu Takeda, Shinjiro Hamano, Atsushi Yamanaka et al. · The Journal of Immunology · 2003 · 530 citations · Full text

Life Sciences, Cell Biology, Immunology +17

IL-27 regulates IL-12 responsiveness of naïve CD4 ⁺ T cells through Stat1-dependent and -independent mechanisms

Sophie Lucas, Nico Ghilardi, Ji Li et al. · Proceedings of the National Academy of Sciences · 2003 · 456 citations · Full text

Life Sciences, Cell Biology, Immunology +17

WSX-1 Is Required for the Initiation of Th1 Responses and Resistance to L. major Infection

Hiroki Yoshida, Shinjiro Hamano, Giorgio Senaldi et al. · Immunity · 2001 · 409 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +14