Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

Hiroshi Takayanagi, Sunhwa Kim, Takako Koga, +11

Developmental Cell

Terminal DifferentiationIntegrate Rankl SignalingDevelopmental BiologyBone Morphogenic ProteinCell Signaling +9

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

Nicholas Joza, Santos A. Susín, Éric Daugas, +17

Nature

MitophagyEssential RoleMitochondrial FunctionApoptosisAutophagy +8

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.

Takeshi Itoh, Masatoshi Tanioka, Hiroki Yoshida, +3

PubMed

Gelatinase A-deficient MiceAngiogenesisMatrix ProteolysisMedicineImmunology +12

Autoamplification of NFATc1 expression determines its essential role in bone homeostasis

Masataka Asagiri, Kojiro Sato, Takako Usami, +8

The Journal of Experimental Medicine

SclerostinMolecular BiologyNfatc1 ExpressionImmune SystemCell Specialization +16

Apaf-1 and Caspase-9 in p53-Dependent Apoptosis and Tumor Inhibition

Marı́a S. Soengas, Rodolfo Alarcón, Hiroki Yoshida, +5

Science

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

José Luís de la Pompa, Luika Timmerman, Hiroaki Takimoto, +9

Nature

Cardiac MuscleTranscriptional RegulationNf-atc Transcription FactorDevelopmental BiologyCardiac Valves +8

Anti–Interleukin-31 Receptor A Antibody for Atopic Dermatitis

Thomas Ruzicka, Jon M. Hanifin, Masutaka Furue, +9

New England Journal of Medicine

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

Atsunobu Takeda, Shinjiro Hamano, Atsushi Yamanaka, +5

The Journal of Immunology

T-regulatory CellImmunologyImmune RegulationImmunologic MechanismCd4 T Cell Responses +19

The IL-27R (WSX-1) Is Required to Suppress T Cell Hyperactivity during Infection

Alejandro V. Villarino, Linda Hibbert, Linda A. Lieberman, +6

Immunity

InflammationAutoimmune DiseaseT-regulatory CellImmune RegulationImmunology +4

Genetic Evidence for Functional Redundancy of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1): CD31-Deficient Mice Reveal PECAM-1-Dependent and PECAM-1-Independent Functions

Gordon S. Duncan, David P. Andrew, Hiroaki Takimoto, +11

The Journal of Immunology

Cell AdhesionImmunologyBlood CellCellular PhysiologyInflammation +21