Concepedia

Synthesis and biological evaluation of C-glucosides with azulene rings as selective SGLT2 inhibitors for the treatment of type 2 diabetes mellitus: Discovery of YM543

Kazuhiro Ikegai, Masakazu Imamura, Takayuki Suzuki, Keita Nakanishi, Takeshi Murakami, Eiji Kurosaki, Atsushi Noda, Yoshinori Kobayashi, Masayuki Yokota, Tomokazu Koide,

Bioorganic & Medicinal Chemistry · 2013 · 52 citations · 48 references

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48

Global Prevalence of Diabetes

Sarah H. Wild, Gojka Roglić, Anders Green et al. · Diabetes Care · 2004 · 15.3K citations

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Hepatogastroenterology

Dong Hyun Sinn, Jeong Kim, Su Rin Shin et al. · Hepatogastroenterology · 2011 · 663 citations

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Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995–2005: a population-based study

Lorraine L. Lipscombe, Janet E. Hux · The Lancet · 2007 · 635 citations

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Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Wei Meng, Bruce A. Ellsworth, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2008 · 628 citations · Full text

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The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

Y. Kanai, W S Lee, Dennis Brown et al. · Journal of Clinical Investigation · 1994 · 624 citations · Full text

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