DNase use in the daily care of cystic fibrosis: who benefits from it and to what extent? Results of a cohort study of 199 patients in 13 centres

Efficacy and Safety of Short-term Administration of Aerosolized Recombinant Human Deoxyribonuclease in Patients with Cystic Fibrosis

Bonnie W. Ramsey, Susan J. Astley, Moira L. Aitken et al. · American Review of Respiratory Disease · 1993 · 234 citations

Medicine, Pharmacotherapy, Pediatric Pulmonology +14

Recombinant human DNase I in cystic fibrosis patients with severe pulmonary disease: a short-term, double-blind study followed by six months open-label treatment

Andrew Bush, GJ Canny, AA Colin et al. · European Respiratory Journal · 1995 · 88 citations · Full text

Medicine, Molecular Biology, Pharmacotherapy +14

Two years experience with recombinant Human DNase I in the treatment of pulmonary disease in cystic fibrosis

Pallav L. Shah, Sandra Scott, DM Geddes et al. · Respiratory Medicine · 1995 · 67 citations · Full text

Medicine, Biotechnology, Molecular Biology +11

Effect of nebulised recombinant DNase on neutrophil elastase load in cystic fibrosis.

Christine Costello, C. M. O’Connor, Geraldine A. Finlay et al. · Thorax · 1996 · 32 citations · Full text

Life Sciences, Immunology, Molecular Biology +6

Aerosolized rhDNase in cystic fibrosis: effect on leucocyte proteases in sputum

Thierry Rochat, FD Pastore, SE Schlegel-Haueter et al. · European Respiratory Journal · 1996 · 31 citations · Full text

Life Sciences, Biochemistry, Immunology +12