Measurement of enzyme kinetics and inhibitor constants using enthalpy arrays

Smoothing and Differentiation of Data by Simplified Least Squares Procedures.

Abraham. Savitzky, Marcel J. E. Golay · Analytical Chemistry · 1964 · 20.7K citations

Altmetrics, Engineering, Filtering Technique +14

Structure and Mechanism in Protein Science. A guide to Enzyme Catalysis and Protein Folding

J.L. Howland · Biochemistry and Molecular Biology Education · 2001 · 1.8K citations

Protein Chemistry, Protein Assembly, Biochemistry +6

A spectrophotometric determination of trypsin and chymotrypsin

George W. Schwert, Yasuo Takenaka · Biochimica et Biophysica Acta · 1955 · 1.5K citations

Spectrophotometric Determination, Medicine, Bioanalysis +4

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

Takashi Chijiwa, Akihiko Mishima, Masatoshi Hagiwara et al. · Journal of Biological Chemistry · 1990 · 1.5K citations · Full text

Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.

Bruce E. Kemp, D J Graves, E. Benjamini et al. · Journal of Biological Chemistry · 1977 · 847 citations · Full text

Protein Function, Signal Transduction, Molecular Physiology +12