Differences in the intrinsic immunogenicity and allergenicity of <scp>B</scp> et v 1 and related food allergens revealed by site‐directed mutagenesis

Abstract

These findings lead to the suggestion that the Bet v 1 structure has unique intrinsic properties, which could account for its high allergenicity. Obviously, these characteristics are not entirely shared with its food homologues from apple and hazelnut. Thus, it is important to tackle pollen-related food allergies from different angles for the generation of effective vaccine candidates to treat birch PFS.