Evaluation of 9-[(3-18F-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG) in vitro and in vivo as a probe for PET imaging of gene incorporation and expression in tumors

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine

Gertrude B. Elion, Phillip A. Furman, James A. Fyfe et al. · Proceedings of the National Academy of Sciences · 1977 · 1.6K citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

Kenneth W. Culver, Zvi Ram, Stuart Wallbridge et al. · Science · 1992 · 1.5K citations

Medicine, Cancer Biology, Oncology +17

9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes group

H. J. Schaeffer, Lilia M. Beauchamp, P de Miranda et al. · Nature · 1978 · 1.1K citations

Life Sciences, Biology, Microbiology +8

(E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.

Erik De Clercq, J Descamps, P. De Somer et al. · Proceedings of the National Academy of Sciences · 1979 · 482 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats.

Zvi Ram, Kenneth W. Culver, Stuart Walbridge et al. · PubMed · 1993 · 437 citations

Medicine, Oncology, Pharmacology +17