Two-step enzymatic synthesis of ursodeoxycholic acid with a new 7β-hydroxysteroid dehydrogenase from Ruminococcus torques

Crystal Structures of the Binary and Ternary Complexes of 7α-Hydroxysteroid Dehydrogenase from <i>Escherichia coli</i>^,

Nobutada Tanaka, Takamasa Nonaka, Tetsurou Tanabe et al. · Biochemistry · 1996 · 236 citations

Life Sciences, Biochemistry, Molecular Biology +17

The Preparation of Chenodeoxycholic Acid and Its Glycine and Taurine Conjugates.

Alan F. Hofmann, Georg Lundgren, Olof Theander et al. · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1963 · 212 citations · Full text

Life Sciences, Biochemistry, Pharmacology +10

Contribution of the 7β-hydroxysteroid dehydrogenase from Ruminococcus gnavus N53 to ursodeoxycholic acid formation in the human colon

Jayoung Lee, Hisashi Arai, Yusuke Nakamura et al. · Journal of Lipid Research · 2013 · 180 citations · Full text

Life Sciences, Biochemistry, Microbiology +11

A two-year prospective study of the effect of ursodeoxycholic acid on urinary bile acid excretion and liver morphology in cystic fibrosis-associated liver disease

Anders Lindblad, Hans Glaumann, Birgitta Strandvik · Hepatology · 1998 · 174 citations · Full text

Medicine, Biochemistry, Internal Medicine +17

Cloning and sequencing of a bile acid-inducible operon from Eubacterium sp. strain VPI 12708

Darrell H. Mallonee, W B White, P B Hylemon · Journal of Bacteriology · 1990 · 110 citations · Full text

Life Sciences, Microbiology, Molecular Biology +10