Design of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

David L. Porter, Bruce L. Levine, Michael Kalos et al. · New England Journal of Medicine · 2011 · 3.5K citations · Full text

Life Sciences, Hematology, Immunology +17

Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes

Richard A. Morgan, Mark E. Dudley, John R. Wunderlich et al. · Science · 2006 · 2.6K citations · Full text

Medicine, Immunology, Oncology +14

Plat-E: an efficient and stable system for transient packaging of retroviruses

S. Morita, T Kojima, Toshio Kitamura · Gene Therapy · 2000 · 1.7K citations

Life Sciences, Biology, Biotechnology +9

Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors.

Zelig Eshhar, Tova Waks, G. Gross et al. · Proceedings of the National Academy of Sciences · 1993 · 1.6K citations

Life Sciences, Immunology, Oncology +17

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Laura A. Johnson, Richard A. Morgan, Mark E. Dudley et al. · Blood · 2009 · 1.4K citations · Full text

Medicine, Cancer Biology, Oncology +17