Mechanism of the beneficial effects of ATP-MgCl2 following trauma-hemorrhage and resuscitation: Downregulation of inflammatory cytokine (TNF, IL-6) release

Shock and Tissue Injury Induced by Recombinant Human Cachectin

Kevin J. Tracey, Bruce Beutler, Stephen F. Lowry et al. · Science · 1986 · 2.6K citations

Lung Inflammation, Immunology, Cell Death +18

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

Kevin J. Tracey, Yuman Fong, David Hesse et al. · Nature · 1987 · 2.5K citations

Humoral Response, Immunology, Sepsis +5

A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes

Terje Espevik · Journal of Immunological Methods · 1986 · 1.3K citations

Inflammation, Cytokine, Clone 13 +11

High circulating levels of interleukin-6 in patients with septic shock: Evolution during sepsis, prognostic value, and interplay with other cytokines

Thierry Calandra, J. Gérain, Didier Heumann et al. · The American Journal of Medicine · 1991 · 447 citations

Inflammation, Cytokine, High Circulating Levels +10

Anti-IL-6 monoclonal antibodies protect against lethal <i>Escherichia coli</i> infection and lethal tumor necrosis factor-<i>alpha</i> challenge in mice.

H. Fletcher Starnes, M K Pearce, Anita Tewari et al. · The Journal of Immunology · 1990 · 325 citations